Tan Kian Meng-Lai Pei Jing, Malaysia's sole representatives in the mixed doubles in the USD350,000 OUE Singapore Open cleared the first hurdle with a 21-18, 21-16 win over Thailand's Bodin Isara-Savitree Amitrapai at the Indoor Stadium on Tuesday.
The eighth seeded Malaysians next play Hong Kong's Tam Chun Hei-Ng Tsz Yau in the second round for a place in the quarter-finals.
Malaysia were forced to withdraw two other mixed doubles pairs from the Singapore Open due to injuries.
World No 6 Chan Peng Soon-Goh Liu Ying who won the silver medal at last year's Rio Olympics and finished runners-up in the All-England Championships last month wihdrew after Liu Ying aggravated her injured right hand during last week's Celcome Axiata Malaysia Open in Kuching, Sarawak.
Goh Soon Huat-Shevon Lai Jemie also withdrew from the Singapore Open. The pair also conceded a walkover in the Malaysia Open after Soon Huat injured his right ankle during training a day before the tournament began.
Meanwhile, Olympic champions Tontowi Ahmad and Liliyana Natsir suffered a shock defeat in the first round in the Singapore. The Indonesians, ranked No 3 in the world, fell to a 21-14, 21-16 defeat to Thailand's Dechapol Puavaranukrih-Sapsiree Taerattanachai.
The Indonesians were beaten semi-finalists in the Malsysia Open. They were also beaten semi-finalists in last year's Singapore Open.